July 22, 202621 games on slate
MLB Picks Today
All of today's MLB picks in one place. Expert moneyline, run line, and total picks across the full slate with confidence ratings and statistical analysis.
Top Picks Today
MLB Picks Today — Full Table
| Time | Matchup | Our Pick | Confidence |
|---|---|---|---|
| 00:05 | Chicago White Sox @ Texas Rangers | Sox Moneyline | 73% |
| 00:05 | Detroit Tigers @ Chicago Cubs | Cubs Moneyline | 47% |
| 00:10 | Miami Marlins @ Houston Astros | Astros Moneyline | 56% |
| 00:40 | Washington Nationals @ Colorado Rockies | Nationals Moneyline | 49% |
| 01:38 | St.Louis Cardinals @ Los Angeles Angels | Cardinals Moneyline | 62% |
| 01:40 | Cincinnati Reds @ Seattle Mariners | Mariners Moneyline | 50% |
| 01:40 | Athletics @ Arizona Diamondbacks | Diamondbacks Moneyline | 59% |
| 17:05 | Pittsburgh Pirates @ New York Yankees | Pirates Moneyline | 55% |
| 17:35 | Baltimore Orioles @ Boston Red Sox | Sox Moneyline | 64% |
| 18:10 | New York Mets @ Milwaukee Brewers | Brewers Moneyline | 69% |
| 18:10 | San Francisco Giants @ Kansas City Royals | Royals Moneyline | 49% |
| 19:10 | Washington Nationals @ Colorado Rockies | Nationals Moneyline | 49% |
| 19:40 | Cincinnati Reds @ Seattle Mariners | Mariners Moneyline | 50% |
| 19:40 | Athletics @ Arizona Diamondbacks | Diamondbacks Moneyline | 59% |
| 20:07 | St.Louis Cardinals @ Los Angeles Angels | Angels Moneyline | 55% |
| 22:40 | Los Angeles Dodgers @ Philadelphia Phillies | Dodgers Moneyline | 38% |
| 22:40 | Minnesota Twins @ Cleveland Guardians | Guardians Moneyline | 45% |
| 23:05 | Pittsburgh Pirates @ New York Yankees | Pirates Moneyline | 53% |
| 23:07 | Tampa Bay Rays @ Toronto Blue Jays | Rays Moneyline | 71% |
| 23:10 | Baltimore Orioles @ Boston Red Sox | Sox Moneyline | 63% |
| 23:15 | San Diego Padres @ Atlanta Braves | Braves Moneyline | 46% |
Game-by-Game Odds & Picks
Chicago White Sox vs Texas Rangers
00:05
Best Bet: Over 8.5
| Team | Moneyline | Run Line | Total | Impl. Prob. |
|---|---|---|---|---|
Chicago White SoxAway | -105 | -208 | -118 | 51% |
Texas RangersHome | -116 | +166 | -105 | 54% |
Odds via API-SportsTotal: O/U 8.5
Detroit Tigers vs Chicago Cubs
00:05
Best Bet: Over 7.5
| Team | Moneyline | Run Line | Total | Impl. Prob. |
|---|---|---|---|---|
Detroit TigersAway | +100 | -217 | -110 | 50% |
Chicago CubsHome | -120 | +163 | -111 | 55% |
Odds via API-SportsTotal: O/U 7.5
Miami Marlins vs Houston Astros
00:10
Best Bet: Under 9
| Team | Moneyline | Run Line | Total | Impl. Prob. |
|---|---|---|---|---|
Miami MarlinsAway | +105 | -200 | -120 | 49% |
Houston AstrosHome | -125 | +160 | -102 | 56% |
Odds via API-SportsTotal: O/U 9
Washington Nationals vs Colorado Rockies
00:40
Best Bet: Under 13
| Team | Moneyline | Run Line | Total | Impl. Prob. |
|---|---|---|---|---|
Washington NationalsAway | -111 | -227 | -112 | 53% |
Colorado RockiesHome | -105 | +161 | -106 | 51% |
Odds via API-SportsTotal: O/U 13
St.Louis Cardinals vs Los Angeles Angels
01:38
Best Bet: Under 9
| Team | Moneyline | Run Line | Total | Impl. Prob. |
|---|---|---|---|---|
St.Louis CardinalsAway | +100 | -208 | -120 | 50% |
Los Angeles AngelsHome | -120 | +159 | -102 | 55% |
Odds via API-SportsTotal: O/U 9
Cincinnati Reds vs Seattle Mariners
01:40
Best Bet: Over 7.5
| Team | Moneyline | Run Line | Total | Impl. Prob. |
|---|---|---|---|---|
Cincinnati RedsAway | +100 | -227 | -109 | 50% |
Seattle MarinersHome | -118 | +172 | -111 | 54% |
Odds via API-SportsTotal: O/U 7.5
MLB Picks Today — Expert Analysis
Our MLB picks today cover every game on today's slate. Each pick is supported by win percentage data, current form, and odds comparison. We present picks across all three major betting markets — moneyline, run line, and game total — so you can find the best value regardless of your preferred betting style.
Our picks are generated from live MLB standings, win percentages, head-to-head trends, and pitching matchup data. All odds are approximate — always confirm current lines at your preferred sportsbook before wagering.